Altered avalanche dynamics in a developmental NMDAR hypofunction model of cognitive impairment
نویسندگان
چکیده
منابع مشابه
A MODEL FOR EVOLUTIONARY DYNAMICS OF WORDS IN A LANGUAGE
Human language, over its evolutionary history, has emerged as one of the fundamental defining characteristic of the modern man. However, this milestone evolutionary process through natural selection has not left any ’linguistic fossils’ that may enable us to trace back the actual course of development of language and its establishment in human societies. Lacking analytical tools to fathom the cr...
متن کاملCholinergic Hypofunction in Presbycusis-Related Tinnitus With Cognitive Function Impairment: Emerging Hypotheses
Shanghai Institute of Geriatrics and Gerontology, Shanghai Key Laboratory of Clinical Geriatrics, Huadong Hospital, and Research Center of Aging and Medicine, Shanghai Medical College, Fudan University, Shanghai, China, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, Department of Otolaryngology, Huadong Hospital, Shanghai Medical College, Fudan University, ...
متن کاملAltered Excitatory-Inhibitory Balance in the NMDA-Hypofunction Model of Schizophrenia
Schizophrenia is a common psychiatric disorder of high incidence, affecting approximately 1% of the world population. The essential neurotransmitter pathology of schizophrenia remains poorly defined, despite huge advances over the past half-century in identifying neurochemical and pathological abnormalities in the disease. The dopamine/serotonin hypothesis has originally provided much of the mo...
متن کاملthe effect of e-64 on the developmental competence of sheep cocs during in vitro maturation
in the present study, the effect of e-64 at different concentrations (0.5, 1, 5 and 10 µm) added to (1) the ivm medium on oocyte nuclear maturation and developmental competence of ovine oocytes, and (2) to the ivc medium on embryonic development of ovine embryos were investigated.
When Is a Developmental Model Not a Developmental Model? Cognitive Developmental Models
A recent paper by Seidenberg and McClelland (1989) describes a computational model of word recognition and naming. The authors claim that it is a developmental model; that is, it explains how word recognition skills are acquired by children. The purpose of this paper is to challenge that claim and, in doing so, to set out a number of criteria against which a model of reading development can be ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Translational Psychiatry
سال: 2018
ISSN: 2158-3188
DOI: 10.1038/s41398-017-0060-z